Pipeline: NS5A

NS5A

Hepatitis C Virus

 

Mode of Action

Inhibition of the NS5A polymerase interferes with the viral replication of the hepatitis C virus. NS5A inhibitor, when used in combination with an NS5B inhibitor, leads to improved prognosis and increased cure rates for HCV patients.

Status

  • Lead Generation

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NS5A domain 1 crystal structure dimers in ribbon representation